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Yhun Yhong Sheen Selected Research

3- ((5- ((1,2,4)triazolo(1,5- a)pyridin- 6- yl)- 4- (6- methylpyridin- 2- yl)thiazol- 2- ylamino)methyl)benzonitrile

10/2011EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells.

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Yhun Yhong Sheen Research Topics

Disease

13Neoplasms (Cancer)
11/2015 - 11/2003
11Breast Neoplasms (Breast Cancer)
11/2015 - 05/2004
6Neoplasm Metastasis (Metastasis)
11/2015 - 10/2011
3Fibrosis (Cirrhosis)
01/2016 - 08/2014
2Lymphoma (Lymphomas)
03/2012 - 02/2012
1Leukemia
02/2016
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2016
1Ureteral Obstruction
05/2015
1Pulmonary Fibrosis (Fibrosing Alveolitis)
05/2015
1Hypoxia (Hypoxemia)
06/2013
1Carcinoma (Carcinomatosis)
07/2010
1Carcinogenesis
07/2010
1Hepatocellular Carcinoma (Hepatoma)
04/2004
1Neuroblastoma
11/2003

Drug/Important Bio-Agent (IBA)

7Phosphotransferases (Kinase)IBA
01/2016 - 10/2011
5Histone Deacetylase InhibitorsIBA
05/2012 - 05/2004
4Transforming Growth Factors (Transforming Growth Factor)IBA
01/2016 - 09/2013
4vactosertibIBA
01/2016 - 07/2014
4Estrogen ReceptorsIBA
05/2012 - 05/2004
33- (4- dimethylaminophenyl)- N- hydroxy- 2- propenamideIBA
05/2012 - 01/2012
3CarcinogensIBA
03/2012 - 07/2010
2Biomarkers (Surrogate Marker)IBA
03/2012 - 02/2012
2ProteomeIBA
03/2012 - 02/2012
2Histone Deacetylases (Histone Deacetylase)IBA
01/2012 - 01/2012
2benzonitrileIBA
11/2011 - 10/2011
2HC toxinIBA
06/2004 - 05/2004
2trichostatin A (A 300)IBA
06/2004 - 05/2004
1Tyrosine Kinase InhibitorsIBA
02/2016
1Therapeutic UsesIBA
11/2015
1Paclitaxel (Taxol)FDA LinkGeneric
11/2015
1Carbon Tetrachloride (Tetrachloromethane)IBA
05/2015
1Bleomycin (Blenoxane)FDA LinkGeneric
05/2015
13- ((5- (6- methylpyridin- 2- yl)- 4- (quinoxalin- 6- yl)- 1H- imidazol- 2- yl)methyl)benzamideIBA
08/2014
1Aldehyde DehydrogenaseIBA
06/2013
1C.I. Solvent Yellow 56 (DEAB)IBA
06/2013
1Estrogen Receptor Modulators (Antiestrogen)IBA
05/2012
1Emodin (Archin)IBA
03/2012
12-nitrotolueneIBA
03/2012
1Mannitol (Osmitrol)FDA LinkGeneric
03/2012
1Ethylene Dibromide (1,2 Dibromoethane)IBA
03/2012
1moesinIBA
02/2012
1EnzymesIBA
01/2012
1Thymidylate SynthaseIBA
01/2012
1Hormones (Hormone)IBA
01/2012
1Apoptosis Regulatory ProteinsIBA
01/2012
1CyclinsIBA
01/2012
13- ((4- ((1,2,4)triazolo(1,5- a)pyridin- 6- yl)- 5- (6- methylpyridin- 2- yl)- 1H- imidazol- 2- yl)methylamino)benzonitrileIBA
11/2011
13- ((5- ((1,2,4)triazolo(1,5- a)pyridin- 6- yl)- 4- (6- methylpyridin- 2- yl)thiazol- 2- ylamino)methyl)benzonitrileIBA
10/2011
1Activin Receptors (Activin Receptor)IBA
10/2011
1Proteins (Proteins, Gene)FDA Link
07/2010
1Melphalan (Alkeran)FDA LinkGeneric
07/2010
1Oncogene Proteins (Oncogene Protein)IBA
07/2010
1Pharmaceutical PreparationsIBA
07/2010
1Caspase 3 (Caspase-3)IBA
06/2004
1Cytochrome P-450 CYP3AIBA
04/2004
1Histones (Histone)IBA
04/2004
1LigandsIBA
11/2003
1PPAR gammaIBA
11/2003
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2003

Therapy/Procedure

5Therapeutics
11/2015 - 05/2012
2Ligation
01/2016 - 05/2015
1Drug Therapy (Chemotherapy)
11/2015